Serge Luquet received his undergraduate degree in Biology &Biochemistry from the University of Nice Sophia Antipolis, France in 2003 in the laboratory directed by Dr Paul A Grimaldi. During his PhD training he was interested in the role of the fatty-activated transcription factor PPAR delta in adipose and muscle cell differentiation. He published seminal paper showing the role of PPAR delta in the controls of muscle development and oxidative capability. In 2003 he joined the laboratory of Pr Richard Palmiter (Howard Hughes Medical Institute & Department of Biochemistry) at the University of Washington, Seattle for his post-doctoral training. He studied the role of hypothalamic neurons that produce Agouti related protein in the control of feeding behavior. He was recruited at researcher by the French CNRS in 2006 and was awarded a young investigator research program that led him to conduct an independent research. His group is established at the University Paris 7 Paris Diderot in the unit “Biologie Fonctionnelle et Adaptative “EAC 4413. The core approach of his team is to leverage the power of modern molecular genetic tools and mouse models using integrated approaches in order to dissect out the role of discrete neural circuit elements in the control of different aspect of energy balance including feeding behavior & energy expenditure.